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KMID : 0381219920240010033
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Journal of RIMSK
1992 Volume.24 No. 1 p.33 ~ p.39
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The Changes of Arterial Blood Gas Tension According to Change to Driving Pressure of High pressure of High Frequency Jet Ventilation at Low Pulmonary Surfactant
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Abstract
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High Frequency Jet Ventilation is considered reliable technique for anesthesia and critical care such as various delicate operations or respiratory failure.
The purpose of this study was to investigate the influence of various driving pressure(10 psi ; 517 mmHg~50 psi ; 2585 mmHg) on arterial oxygenation and carbon dioxide elimination. Severe respiratory insufficiency was induced in 8 korean mongrel
dogs by
lung lavage with 0.9% normal saline 20 ml/kg at 37℃. The animals were ventilated for 20 minutes by conventional ventilator with room air, frequency 20/min, tidal volume 10ml/kg, I : E ratio 50% and then High Frequency Jet Ventilator by changing
the
driving pressure from 10 psi to 50 psi with compressed air, frequency 100/min, and I : E ratio 50%. Arterial blood gas tension and cardiovascular variables consisting of systolic and distolic blood pressure, mean arterial pressure, heart rate
were
evaluated.
@ES The results were as follows:
@EN 1) Systolic blood pressure was decreased at 50psi(p<0.01) and diastolic blood pressure and mean arterial pressure was decreased at 40 psi and 50 psi(p<0.01) of high jet ventilation.
2) heart rate was decreased at conventional ventilation(p<0.01) and 10 psi and 20 psi of high frequency jet ventilation(p<0.05).
3) PaO2 was decreased at conventional ventilation(p<0.01), and driving pressure 10 psi(p<0.01) , 20 psi, and 30 phis of high frequency jet ventilation(p<0.05).
4) PaCO2 was increased at conventional ventilation and high frequency jet ventilation 10 psi (p<0.01), but PaCO2 was proportionally decreased above 20 psi(p<0.01).
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KEYWORD
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